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Healing & Recovery
Phase 2

AOD-9604

AOD-9604

Also known as: AOD9604, Anti-Obesity Drug 9604, Tyr-hGH Fragment 177-191

Overview

Key Facts

Primary Goal: Research and therapeutic applications of AOD-9604

Mimics the lipolytic domain of GH by activating beta-3 adrenergic receptor-mediated fat metabolism. Inhibits lipogenesis through suppression of key adipogenic transcription factors.

Dosing Information

Half-Life

~30 minutes

Typical Dose

250–500 mcg

Frequency

once daily, fasted

Cycle Length

12-24 weeks

Administration Routes:
subcutaneousoral

Benefits

  • Stimulates lipolysis (fat breakdown) similar to natural GH
  • Does not affect blood glucose or insulin sensitivity
  • No effect on IGF-1 levels, minimizing growth-related side effects
  • Inhibits lipogenesis (new fat formation)
  • May support cartilage repair based on emerging research

Side Effects

Mild headachemild
Injection site reactionsmild
Occasional nauseamild

Mechanism of Action

1

Mimics the lipolytic domain of GH by activating beta-3 adrenergic receptor-mediated fat metabolism

2

Inhibits lipogenesis through suppression of key adipogenic transcription factors

3

Does not bind the GH receptor or stimulate IGF-1 production

Contraindications

Do not use this peptide if any of the following apply:

  • Active malignancy
  • Pregnancy or breastfeeding
  • Known hypersensitivity to the compound

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F)
DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)
Duration2-4 weeks

Research Summary

Phase 2

AOD-9604 underwent Phase II clinical trials for obesity showing modest but statistically significant fat loss compared to placebo. It received GRAS (Generally Recognized as Safe) status from the FDA in 2014 for use as a food substance. Recent research has pivoted toward its potential in cartilage regeneration and osteoarthritis treatment.

Frequently Asked Questions

Common questions about AOD-9604

UK-Specific Information

Exclusive data points and guidance for UK residents using AOD-9604

UK Lab Testing

UK Lab Testing

Recommended labs: Medichecks, Thriva (£89-£149 for peptide safety panel)

Why this matters: UK-specific lab testing guidance not available on US competitor sites

Commonly Stacked With

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