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Healing & Recovery
Preclinical

Pinealon

Pinealon

Also known as: EDR peptide, Glu-Asp-Arg, Brain Bioregulator

Overview

Key Facts

Primary Goal: Research and therapeutic applications of Pinealon

Modulates gene expression in neuronal cells to promote survival pathways. Enhances antioxidant defense in brain tissue.

Dosing Information

Half-Life

~1-2 hours

Typical Dose

5–10 mg

Frequency

Once daily for 10-15 day cycles

Cycle Length

10-15 days on, 3-6 months off

Administration Routes:
subcutaneousoral

Benefits

  • Neuroprotective effects against oxidative stress
  • Supports cognitive function and memory in ageing
  • Regulates pineal gland function and melatonin synthesis
  • Promotes neuronal survival under stress conditions
  • May improve sleep quality through circadian regulation

Side Effects

Mild drowsinessmild
Occasional headachemild
Generally very well toleratedmild

Mechanism of Action

1

Modulates gene expression in neuronal cells to promote survival pathways

2

Enhances antioxidant defence in brain tissue

3

Regulates pineal gland peptide and melatonin production

4

Supports synaptic plasticity and neurotransmitter balance

Contraindications

Do not use this peptide if any of the following apply:

  • Active neurological conditions requiring medication (consult physician)
  • Concurrent use of sedatives or CNS depressants (may potentiate effects)
  • Pregnancy or breastfeeding

Storage & Reconstitution

Unreconstituted (Powder)

Temperature15–25°C (59–77°F)
DurationUp to 3 months

Reconstituted (Mixed)

Temperature15–25°C (59–77°F)
Duration2-4 weeks

Research Summary

Preclinical

Preclinical studies have demonstrated that Pinealon protects neurons from hypoxia-induced and oxidative damage, promoting cell survival in cortical neuron cultures. Gene expression studies show modulation of apoptosis-related genes and antioxidant enzymes. In aged animal models, Pinealon courses improved learning, memory, and neuronal density. Part of the Khavinson bioregulator programme that has produced over 200 publications on short peptide bioregulation. No large-scale Western clinical trials to date.

Frequently Asked Questions

Common questions about Pinealon

UK-Specific Information

Exclusive data points and guidance for UK residents using Pinealon

UK Lab Testing

UK Lab Testing

Recommended labs: Medichecks, Thriva (£89-£149 for peptide safety panel)

Why this matters: UK-specific lab testing guidance not available on US competitor sites

Commonly Stacked With

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