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Healing & Recovery
Preclinical

Selank

Selank

Also known as: TP-7, Selanc

Overview

Key Facts

Primary Goal: Research and therapeutic applications of Selank

Modulates GABAergic neurotransmission, enhancing inhibitory signaling without direct GABA-A receptor binding. Influences expression of BDNF and serotonin transporter genes.

Dosing Information

Half-Life

~several minutes (active metabolites persist 3-5 hours)

Typical Dose

150–500 mcg

Frequency

1-3 times daily

Cycle Length

14-30 days

Administration Routes:
subcutaneous

Benefits

  • Anxiolytic effects comparable to benzodiazepines without sedation or dependence
  • Enhanced memory consolidation and learning
  • Immunomodulatory activity via tuftsin backbone
  • Improved emotional stability and stress resilience
  • Increased IL-6 expression and immune system regulation

Side Effects

Mild nasal discomfort with intranasal administrationmild
Occasional fatigue during initial usemild
Rare reports of mild headachemild

Mechanism of Action

1

Modulates GABAergic neurotransmission, enhancing inhibitory signaling without direct GABA-A receptor binding

2

Influences expression of BDNF and serotonin transporter genes

3

Tuftsin backbone activates phagocytic immune cells and modulates cytokine expression

4

Stabilizes enkephalin degradation, indirectly enhancing endogenous opioid tone

Contraindications

Do not use this peptide if any of the following apply:

  • Pregnancy or breastfeeding
  • Active autoimmune conditions (due to immunomodulatory effects)
  • Known hypersensitivity to tuftsin-derived compounds

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F)
DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)
Duration2-4 weeks

Research Summary

Preclinical

Selank was approved in Russia in 2009 for generalized anxiety disorder and as a nootropic. Clinical studies demonstrated anxiolytic efficacy comparable to medazepam (a benzodiazepine) without sedation, cognitive impairment, or withdrawal symptoms. Research has confirmed its influence on over 50 genes related to GABAergic signaling, serotonin transport, and immune function. Its dual anxiolytic-immunomodulatory profile is unique among peptide-based compounds.

Frequently Asked Questions

Common questions about Selank

UK-Specific Information

Exclusive data points and guidance for UK residents using Selank

UK Lab Testing

UK Lab Testing

Recommended labs: Medichecks, Thriva (£89-£149 for peptide safety panel)

Why this matters: UK-specific lab testing guidance not available on US competitor sites

Commonly Stacked With

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