Tesofensine
Tesofensine
Also known as: NS2330, Tesomet
Overview
Key Facts
Primary Goal: Research and therapeutic applications of Tesofensine
Inhibits reuptake of norepinephrine, dopamine, and serotonin. Enhances sympathetic nervous system activity to boost thermogenesis.
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Compare Tesofensine prices →Dosing Information
~200-300 hours
0.25–1 mg
Once daily (oral)
12-24 weeks under medical supervision
Benefits
- Potent appetite suppression
- Increased resting metabolic rate and thermogenesis
- Potential cognitive enhancement effects
- Significant weight loss observed in clinical trials (up to 12%)
Side Effects
Mechanism of Action
Inhibits reuptake of norepinephrine, dopamine, and serotonin
Enhances sympathetic nervous system activity to boost thermogenesis
Modulates hypothalamic appetite regulation via monoamine signaling
Contraindications
Do not use this peptide if any of the following apply:
- Uncontrolled hypertension or cardiovascular disease
- History of stroke or heart attack
- Concurrent use of MAO inhibitors or other stimulants
- Anxiety disorders or insomnia
- Pregnancy or breastfeeding
Storage & Reconstitution
Unreconstituted (Powder)
Reconstituted (Mixed)
For suppliers & labs
Building a Tesofensine catalogue? Custom waterproof vial & pen labels (zero MOQ, UK print) on PepPrint →
Research Summary
Phase 2 trials demonstrated that tesofensine 0.5 mg produced approximately 12.8% body weight loss over 24 weeks, roughly double that of existing anti-obesity medications at the time. Phase 3 trials (TESORA) are ongoing in several countries. The compound also showed improvements in metabolic parameters including HbA1c and lipid profiles. Cardiovascular safety monitoring remains a key focus.
Frequently Asked Questions
Common questions about Tesofensine
UK-Specific Information
Exclusive data points and guidance for UK residents using Tesofensine
UK Lab Testing
UK Lab Testing
Recommended labs: Medichecks, Thriva (£89-£149 for peptide safety panel)
Why this matters: UK-specific lab testing guidance not available on US competitor sites
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Note: Peptide stacking should only be done under the guidance of a qualified healthcare professional. Individual responses may vary.
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