What is the half-life of TB-500 (Immune)?

TB-500 (Immune) has a half-life of ~2 hours, which is why it's typically administered 2x per week (loading), 1x per week (maintenance) for optimal therapeutic effect.

How do I reconstitute TB-500 (Immune)?

Add bacteriostatic water to the peptide vial slowly down the side. Typical reconstitution uses 2-3ml of water for a 5mg vial. Gently swirl, do not shake.

Healing & Recovery

Phase 2

TB-500 (Immune)

Also known as: TB4, Thymosin Beta-4, Tβ4

Overview

Key Facts

Primary Goal: A 43-amino acid peptide ubiquitous in human cells, originally identified in the thymus

A 43-amino acid peptide ubiquitous in human cells, originally identified in the thymus. While primarily known for tissue repair (see healing-recovery category), TB-500 also plays a significant role in immune regulation through modulation of inflammatory pathways and immune cell migration. Half-Life ~2 hours Typical Dose 2–5 mg Frequency 2x per week (loading), 1x per week (maintenance) Cycle Length 4-8 weeks loading, then maintenance

Dosing Information

Half-Life

~2 hours

Typical Dose

2–5 mg

Frequency

2x per week (loading), 1x per week (maintenance)

Cycle Length

4-8 weeks loading, then maintenance

Administration Routes:

subcutaneousintramuscular

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F) or -20°C (-4°F) for long-term

DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)

Duration2-3 weeks

Research Summary

Phase 2

Thymosin Beta-4 was originally isolated from the thymus and has well-documented immune-modulatory properties alongside its healing effects. Clinical trials by RegeneRx Biopharmaceuticals have explored its role in wound healing and tissue repair, with immune modulation being a key secondary mechanism. Cross-reference: see tb-500 in healing-recovery for full tissue repair profile.