What is the half-life of TB4-FRAG?

TB4-FRAG has a half-life of ~1 hour, which is why it's typically administered 1x daily or every other day for optimal therapeutic effect.

How do I reconstitute TB4-FRAG?

Add bacteriostatic water to the peptide vial slowly down the side. Typical reconstitution uses 2-3ml of water for a 5mg vial. Gently swirl, do not shake.

Healing & Recovery

Preclinical

TB4-FRAG

Also known as: TB-500 Fragment, TB4 Fragment 17-23, Ac-LKKTETQ

Overview

Key Facts

Primary Goal: An active fragment of Thymosin Beta-4 encompassing the actin-binding domain

An active fragment of Thymosin Beta-4 encompassing the actin-binding domain. Retains key healing properties of the full molecule in a smaller, more targeted form with potentially improved tissue-specific activity. Half-Life ~1 hour Typical Dose 250–750 mcg Frequency 1x daily or every other day Cycle Length 4-8 weeks

Dosing Information

Half-Life

~1 hour

Typical Dose

250–750 mcg

Frequency

1x daily or every other day

Cycle Length

4-8 weeks

Administration Routes:

subcutaneousintramuscular

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F) or -20°C (-4°F) for long-term

DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)

Duration2 weeks

Research Summary

Preclinical

Preclinical research indicates that the active fragment retains the core actin-binding and cell-migration-promoting properties of full-length Thymosin Beta-4. Limited human data; primarily studied in vitro and in animal models.